BRCAS

Dr. Daryi Wang

Ph.D.－National Taiwan Ocean University, 1999

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Office: Interdisciplinary Research Building for Science and Technology A303

Tel:+886-2-2787-2271

• Metagenomics
• Evolutionary genomics

Research Directions

• 1.Construction of microbial interaction network
  Ecological interactions are key factors in understanding both ecology and evolution of animals. Likewise, Microorganisms do not exist solely but form complex ecological interaction network. Thanks to the advancements in sequencing technology, metagenomics, a direct sequencing of DNA from bacterial communities, provides access to the composition and diversity of microbial community in various environments. With a network approach, we take the advantage of metagenomic data and document the interactions between taxa across diverse communities and explore the environmental niches occupied by microorganism. Ultimately, the interaction network will be used to predict the outcome of community alteration and the effects of perturbations, ultimately help with the engineering of complex microbial communities.
• 2.Evolution of gene regulation
  ENCODE project has drawn a great attention, it was shown that a significant fraction of the eukaryotic genome is transcribed into RNAs without further translation. These non-coding RNAs were considered to play an important in regulatory evolution, therefore, a great amount of scientific resource has been devoted to the related researches. We are interested in the antisense transcript which is a single-stranded non-coding RNA complementary to messenger RNA. Antisense RNA is speculated to play an important role in gene regulation through the complimentary interaction. We aimed to investigate the emergence and evolution of this particular transcript using yeast as model organism.