Biodiversity Research Center, Academia Sinica

Dr. Daryi Wang Associate Research Fellow

Lab PI

Dr. Daryi Wang

Associate Research Fellow

Ph.D.-National Taiwan Ocean University, 1999

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Office: Interdisciplinary Research Building for Science and Technology A303


Research Fields
  • Metagenomics
  • Evolutionary genomics

Research Directions

  • 1.Construction of microbial interaction network
    Ecological interactions are key factors in understanding both ecology and evolution of animals. Likewise, Microorganisms do not exist solely but form complex ecological interaction network. Thanks to the advancements in sequencing technology, metagenomics, a direct sequencing of DNA from bacterial communities, provides access to the composition and diversity of microbial community in various environments. With a network approach, we take the advantage of metagenomic data and document the interactions between taxa across diverse communities and explore the environmental niches occupied by microorganism. Ultimately, the interaction network will be used to predict the outcome of community alteration and the effects of perturbations, ultimately help with the engineering of complex microbial communities.
  • 2.Evolution of gene regulation
    ENCODE project has drawn a great attention, it was shown that a significant fraction of the eukaryotic genome is transcribed into RNAs without further translation. These non-coding RNAs were considered to play an important in regulatory evolution, therefore, a great amount of scientific resource has been devoted to the related researches. We are interested in the antisense transcript which is a single-stranded non-coding RNA complementary to messenger RNA. Antisense RNA is speculated to play an important role in gene regulation through the complimentary interaction. We aimed to investigate the emergence and evolution of this particular transcript using yeast as model organism.


Latest published paper

Publications ( 2015-2018 )
  1. Weng, F.C.H., Shaw, G.T.W., Weng, C.Y., Yang, Y.J., Wang, D.*, 2017, “Inferring Microbial Interactions in the Gut of the Hong Kong Whipping Frog (Polypedates megacephalus) and a Validation Using Probiotics”, FRONTIERS IN MICROBIOLOGY, 8, 525-526. (SCI) (IF: 4.076; SCI ranking: 20.8%)
  2. Chen CY, Chen PC, Weng FC, Shaw GT, Wang D, 2017, “Habitat and indigenous gut microbes contribute to the plasticity of gut microbiome in oriental river prawn during rapid environmental change.”, PloS one, 12(7), e0181427. (SCI) (IF: 2.806; SCI ranking: 23.4%)
  3. Shaw GT, Liu AC, Weng CY, Chou CY, Wang D, 2017, “Inferring microbial interactions in thermophilic and mesophilic anaerobic digestion of hog waste.”, PloS one, 12(7), e0181395. (SCI) (IF: 2.806; SCI ranking: 23.4%)
  4. Weng Francis Cheng-Hsuan, Yang Yi-Ju, Wang Daryi*, 2016, “Functional analysis for gut microbes of the brown tree frog (Polypedates megacephalus) in artificial hibernation”, BMC Genomics, 17(S13), 31-42. (SCI) (IF: 3.729; SCI ranking: 21.9%,29.9%)
  5. Shaw Grace Tzun-Wen, Pao Yueh-Yang, Wang Daryi*, 2016, “MetaMIS: a metagenomic microbial interaction simulator based on microbial community profiles”, BMC Bioinformatics, 17(1), 2-6. (SCI) (IF: 2.448; SCI ranking: 17.5%,42.5%,48.7%)
  6. Tzeng, T.D., Pao, Y.Y., Chen, P.C., Weng, F.C.H., Jean, W.D., Wang, D.*, 2015, “Effects of host phylogeny and habitats on gut microbiomes of oriental river prawn (Macrobrachium nipponense).”, PLoS One, 10(7), e0132860. (SCI) (IF: 2.806; SCI ranking: 23.4%)
  7. Tsai, K.N., Lin, S.H., Liu, W.C., Wang, D.*, 2015, “Inferring microbial interaction network from microbiomic data using RMN algorithm”, BMC System biology, 9, 54. (SCI) (IF: 2.303; SCI ranking: 19.3%)
  8. Chen PC, Shih CH, Chu TJ, Wang D, Lee YC, Tzeng TD, 2015, “Population Structure and Historical Demography of the Oriental River Prawn (Macrobrachium nipponense) in Taiwan.”, PloS one, 10(12), e0145927. (SCI) (IF: 2.806; SCI ranking: 23.4%)

Lab members

電  話

邵遵文    翁杰愔    陳政宇

陳忠凱    羅翊菁

翁正軒     黎美幸    蒙國杰