厭氧及極端微生物、微生物代謝多樣性、微生物之生理生態研究、環境體學分析
我的主要研究興趣是微生物代謝多樣性。目前著重於極端微生物的生理與代謝研究。極端微生物是偏好在極端環境中生長繁殖的一群微生物,通常爲單細胞原核或真核生物。極端環境係指不適合脊椎動物生活之環境,包括缺乏氧氣、極端溫度、極端酸鹼值或是高鹽度等特殊理化條件。伴隨新興微生物分析技術之興起,極端微生物之親緣及代謝多樣性研究,近來獲得許多重大進展。相關之微生物乃至酵素或代謝物,具有相當之生醫、農業與工業應用潛力。
期刊論文
- Chen MJ, Chou CH, Hsiao TH, Wu TY, Li CY, Chen YL, ChaoKH, Lee TH, Gicana RG, Shih CJ, Mong GJB, Lai YL, Li PT, Tseng YL, Wang PH, Chiang YR*, 2024, “Clostridium innocuum, an opportunistic gut pathogen, inactivates host gut progesterone and arrests ovarian follicular development”, GUT MICROBES, 16, 2424911. (SCIE) (IF: 12.2; SCI ranking: 9.7%,8.1%)
- Pi HW, Chiang YR, Li WH*, 2024, “Mapping geological events and nitrogen fixation evolution onto the timetree of the evolution of nitrogen-fixation genes”, MOLECULAR BIOLOGY AND EVOLUTION, 39, msae023. (SCIE) (IF: 10.7; SCI ranking: 8.8%,7.5%,5.2%)
- Shota N, Yu WC, Jia T, He MJ, Khusnutdinova A, Yakunin A, Chiang YR, Fujishima K, Wang PH*, 2024, “Amino acid self-regenerating cell-free protein synthesis system that feeds on PLA plastics, CO2, ammonium, and α-ketoglutarate”, ACS CATALYSIS, 14, 7696-7706. (SCIE) (IF: 12.9; SCI ranking: 13.7%)
- Huang TY, Yoon HS, Chiang YR, Fu HY, Watanabe T, Gerung GS, Geraldino PJL, Liu SL*, 2024, “Diversity in Cyanidiophyceae: Cyanidiofrigus pintoensis gen. et sp. nov. within polyextremophilic red algae (Rhodophyta)”, PHYCOLOGIA, 63, 245-259. (SCIE) (IF: 1.6; SCI ranking: 50.5%,62.3%)
- Yi-Jung Sung, Takumi Takahashi, Yi-Hsuan Lin, Tony Z Jia, Yin-Ru Chiang, Po-Hsiang Wang*, 2023, “Microalgal polyphosphate drives one-pot complete enzymatic generation of flavin adenine dinucleotide from adenosine and riboflavin”, ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 12, 680-686. (SCIE) (IF: 9.224; SCI ranking: 16.1%,9.1%,21.3%)
- Tsun-Hsien Hsiao, Po-Hao Chen, Po-Hsiang Wang, Guo-Jie Brandon-Mong, Chen-Wei Li, Masae Horinouchi, Toshiaki Hayashi, Wael Ismail, Menghsiao Meng, Yi-Lung Chen, Yin-Ru Chiang*, 2023, “Harnessing microbial phylum-specific molecular markers for assessment of environmental estrogen degradation”, SCIENCE OF THE TOTAL ENVIRONMENT, 896, 165152. (SCIE) (IF: 10.754; SCI ranking: 9.3%)
- Ma LS*, Lin YH, Xu MY, Hsu CC, Lee HC, Tsai WL, Damei F, Hoang C, Chiang YR, 2023, “Ustilago maydis PR-1-like protein has evolved two distinct domains for dual virulence activities”, Nature Communications, 14, 5755. (SCIE) (IF: 17.694; SCI ranking: 8.1%)
- Gicana RG, Huang MH, Jia TZ, Chiang YR, *Wang PH, 2023, “Upcycling soybean pulp for sustainable amino acid and subsequent protein biomanufacturing via a one-pot thermophilic protease cascade treatment”, CHEMICAL ENGINEERING JOURNAL, 474, 145925. (SCIE) (IF: 16.744; SCI ranking: 2.8%,3.6%)
- Tsun-Hsien Hsiao, Chia-Hong Chou, Yi-Lung Chen, Po-Hsiang Wang, Guo-Jie Brandon-Mong, Tzong-Huei Lee, Tien-Yu Wu, Po-Ting Li, Chen-Wei Li, Yi-Li Lai, Yu-Lin Tseng, Chao-Jen Shih, Po-Hao Chen, Mei-Jou Chenb, Yin-Ru Chiang*, 2023, “Circulating androgen regulation by androgen-catabolizing gut bacteria in male mouse gut”, GUT MICROBES, 15, 2183685. (SCIE) (IF: 9.434; SCI ranking: 16.1%,13.8%)
- Huang E, Yan JS, Gicana RG, Chiang YR, Yeh FI, Huang CC, Wang PH*, 2023, “Valorization of soybean pulp for sustainable α-ketoisocaproate production using engineered Bacillus subtilis whole-cell biocatalyst”, CHEMOSPHERE, 322, 138200. (SCIE) (IF: 8.943; SCI ranking: 11.8%)
- Pi HW, Lin JJ, Chen CA, Wang PH, Chiang YR, Huang CC, Young CC, *Li WH, 2022, “Origin and evolution of nitrogen fixation in prokaryotes”, MOLECULAR BIOLOGY AND EVOLUTION, 39, msac181. (SCIE) (IF: 8.8; SCI ranking: 13.1%,9.6%,8.5%)
- Hsiao G, Chi WC, Chang CH, Chiang YR, Fu YJ, *Lee TH, 2022, “Bioactive pulvinones from a marine algicolous fungus Aspergillus terreus NTU243”, PHYTOCHEMISTRY, 200, 113229. (SCIE) (IF: 4.004; SCI ranking: 54.2%,22.1%)
- Wang PH, Chen YL, Wu TY, Wu YW, Wang TY, Shih CJ, Wei STS, Lai YL, Liu CX, Yu CP, Chiang YR*, 2022, “Omics and mechanistic insights into di-(2-ethylhexyl) phthalate degradation in the O2-fluctuating estuarine sediments.”, CHEMOSPHERE, 299, 134406. (SCIE) (IF: 8.943; SCI ranking: 11.8%)
- Gicana RG, Yeh FI, Hsiao TH, Chiang YR, Yan JS, *Wang PH, 2022, “Valorization of fish waste and sugarcane bagasse for enzyme production by Bacillus megaterium via a circular bioeconomy model”, JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS, 135, 104358. (SCIE) (IF: 5.477; SCI ranking: 23.8%)
- AlDhafiri S, Chiang YR, EL Nayal AM, Abed RMM, Abotalib N, *Wael Ismail, 2022, “Temporal Compositional Shifts in an Activated Sludge Microbiome during Estrone Biodegradation.”, Environmental Science and Pollution Research, 29, 32702-32716. (SCIE) (IF: 5.19; SCI ranking: 31.2%)
- Tsun-Hsien Hsiao, Tzong-Huei Lee, Meng-Rong Chuang, Po-Hsiang Wang, Menghsiao Meng, Masae Horinouchi, Toshiaki Hayashi, Yi-Lung Chen, and Yin-Ru Chiang*, 2022, “Identification of essential β-oxidation genes and corresponding metabolites for estrogen degradation by actinobacteria.”, MICROBIAL BIOTECHNOLOGY, 15, 949-966. (SCIE) (IF: 6.575; SCI ranking: 14.3%,21%)
- Chang CW, Miki T, Ye H, Souissi S, Adrian R, Anneville O, Be'eri-Shlevin Y, Chiang YR, Feuchtmayr H, Ichise S, Kagami M, *Hsieh CH, 2022, “Causal networks of phytoplankton diversity and production are modulated by environmental context.”, NATURE COMMUNICATIONS, 13, 1140. (SCIE) (IF: 17.694; SCI ranking: 8.1%)
- Sean Ting-Shyang Wei, Yi-Lung Chen, Yu-Wei Wu, Tien-Yu Wu, Yi-Li Lai, Po-Hsiang Wang, Wael Ismail, Tzong-Huei Lee, and Yin-Ru Chiang*, 2021, “Integrated multi-omics investigations reveal the key role of synergistic microbial networks in removing plasticizer di-(2-ethylhexyl) phthalate from estuarine sediments.”, MSYSTEMS, 6, e00358-21. (SCIE) (IF: 7.328; SCI ranking: 19.6%)
- Wei-Sheng Huang, Li-Ting Wang, Jwo-Sheng Chen, Yen-Ting Chen, Sean Ting-Shyang Wei, Yin-Ru Chiang, Pei-Ling Wang, Tzong-Huei Lee, Shih-Ting Lin, Lina Huang, Wung Yang Shieh*, 2021, “Vibrio nitrifigilis sp. nov., a marine nitrogen-fixing bacterium isolated from the lagoon sediment of an islet inside an atoll”, ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY, 114, 933-945. (SCIE) (IF: 2.158; SCI ranking: 87.7%)
- Tsun-Hsien Hsiao, Yi-Lung Chen, Menghsiao Meng, Meng-Rong Chuang, Masae Horinouchi, Toshiaki Hayashi, Po-Hsiang Wang, and Yin-Ru Chiang*, 2021, “Mechanistic and phylogenetic insights into actinobacteria-mediated estrogen biodegradation in urban estuarine sediments”, MICROBIAL BIOTECHNOLOGY, 13, 926-949. (SCIE) (IF: 6.575; SCI ranking: 14.3%,21%)
- Chun-Wei Chang, Hao Ye, Takeshi Miki, Ethan R Deyle, Souissi Sami, Orlane Anneville, Rita Adrian, Yin-Ru Chiang, Satoshi Ichise, Michio Kumagai, Shin-Ichiro S Matsuzaki, Fuh-Kwo Shiah, Jiunn-Tzong Wu, Chih-Hao Hsieh, George Sugihara, 2020, “Long-term warming destabilizes aquatic ecosystems through weakening biodiversity-mediated causal networks”, GLOBAL CHANGE BIOLOGY, 26(11), 6413-6423. (SCIE) (IF: 13.212; SCI ranking: 1.5%,2.9%,6.1%)
- Jih-Jung Chen, Shih-Wei Wang, Yin-Ru Chiang, Ka-Lai Pang, Yueh-Hsiung Kuo, Tsai-Yen Shih, and Tzong-Huei Lee, 2020, “Highly oxygenated constituents from a marine alga-derived fungus Aspergillus giganteus NTU967”, MARINE DRUGS, 18(6), 303. (SCIE) (IF: 6.085; SCI ranking: 15.9%,17.2%)
- Po-Hsiang Wang, Yi-Lung Chen, Sean Ting-Shyang Wei, Kan Wu, Tzong-Huei Lee, Tien-Yu Wu, and Yin-Ru Chiang*, 2020, “Retroconversion of estrogens into androgens by bacteria via a cobalamin-mediated methylation”, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 117(3), 1395-1403. (SCIE) (IF: 12.779; SCI ranking: 12.2%)
- Han-Yi Fu, Shao-Lun Liu, Yin-Ru Chiang*, 2020, “Biosynthesis of ascorbic acid as a glucose-induced photoprotective process in the extremophilic red alga Galdieria partita.”, Frontiers in Microbiology, 10, 3005. (SCIE) (IF: 6.064; SCI ranking: 24.6%)
- Yin-Ru Chiang*, Sean Ting-Shyang Wei, Po-Hsiang Wang, Pei-Hsun Wu, Chang-Ping Yu, 2019, “Microbial degradation of steroid sex hormones: Implications for environmental and ecological studies.”, MICROBIAL BIOTECHNOLOGY, DOI: 10.1111/1751-7915.13504. (SCIE) (IF: 6.575; SCI ranking: 14.3%,21%)
- Kan Wu, Tzong-Huei Lee, Yi-Lung Chen, Yu-Sheng Wang, Po-Hsiang Wang, Chang-Ping Yu, Kung-Hui Chu, and Yin-Ru Chiang*, 2019, “Metabolites Involved in Aerobic Degradation of the A and B Rings of Estrogen”, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 85(3), e02223-18. (SCIE) (IF: 5.005; SCI ranking: 28.6%,38.4%)
- Mei-Chuan Chen, Guei-Jane Wang, Yueh-Hsiung Kuo, Yin-Ru Chiang, Ting-Yu Cho, Yu-Ming Ju, Tzong-Huei Lee*, 2019, “Isoprenyl phenolic ethers from the termite nest-derived medicinal fungus Xylaria fimbriata”, JOURNAL OF FOOD AND DRUG ANALYSIS, 27(1),111-117. (SCIE) (IF: 6.157; SCI ranking: 18.8%,16.1%)
電話: +886-2-2787-2251
Email: yinru915gate.sinica.edu.tw
地址: 跨領域B305